Concise and efficient three‐component domino [4+1+1] carbocyclization to highly substituted fluoren‐9‐one derivatives promoted by K2CO3 has been developed under microwave irradiation conditions. The direct bis‐cyanation and aryl amination residing in fluoren‐9‐one framework were achieved in a one‐pot operation. The reaction proceeds at fast rates and can be finished within 30 min, which makes workup convenient to give good to excellent chemical yields. 相似文献
A new and efficient access to (Z)‐N‐(2‐argio‐1‐(1H‐perimidin‐2‐yl)vinyl)benzamide derivatives from readily available substrates in HOAc is described with aid of microwave irradiation. The results of our study provide a simple, straightforward synthetic route to these interesting classes of 2‐substituted perimidines analogs in excellent yields. 相似文献
A green and highly efficient method for the synthesis of polyfunctionalized indoline‐spiro fused pyran derivatives has been established. This reaction was conducted by reacting readily available and inexpensive starting materials, such as isatins, cyclic‐1,3‐dicarbonyl compounds, and malononitrile in aqueous media without any catalysts under microwave irradiation. The present green synthesis shows fascinating properties such as the use of water as the reaction solution, concise one‐pot conditions, short reaction periods (8–14 min), and easy purifications. The synthesis could also set a good example to GAP (Group‐Assistant‐Purification) chemistry in which purification via chromatography can be avoided and the pure products can be easily acquired only by washing the crude products with 95% EtOH. 相似文献
The rational design of nanozymes with superior activities is essential for improving bioassay performances. Herein, nitrogen and boron co-doped graphene nanoribbons(NB-GNRs) are prepared by a hydrothermal method using urea as the nitrogen source and boric acid as the boron source, respectively.The introduction of co-doped and edge structures provides high defects and active sites. The resultant NB-GNRs nanozymes show superior peroxidase-like activities to nitrogen-doped and boron-doped counterpa... 相似文献
A simple and efficient tandem reaction approach was developed for the synthesis of 5-hydroxyhydantoins from one-pot reaction of isatins, phthalic anhydride or succinic anhydride, and 1,3-dimethylurea (1,3-diethylurea). The products were gained through the ring-opening of isatins process. The advantages of this report are simple operation, mild reaction conditions, good yields and easily available raw materials. It was very important for us to obtain the intermediate product and that provided a solid basis for the correct interpretation of the reaction mechanism. 相似文献
This paper aims to study the asymptotic behavior of a fast-slow stochastic dynamical system with singular coefficients, where the fast motion is given by a continuous diffusion process while the slow component is driven by an α-stable noise with α ∈ [1, 2). Using Zvonkin’s transformation and the technique of the Poisson equation, we have that both the strong and weak convergences in the averaging principle are established, which can be viewed as a functional law of large numbers. Then we study the small fluctuations between the original system around its average. We show that the normalized difference converges weakly to an Ornstein-Uhlenbeck type Gaussian process, which is a form of the functional central limit theorem. Furthermore, sharp rates for the above convergences are also obtained, and these convergences are shown to not depend on the regularities of the coefficients with respect to the fast variable, which reflect the effects of noises on the multi-scale systems.